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    5. Issue 8

    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/131/08/0073

    • Keywords

       

      Diorganotin; synthesis; structure; anticancer activity

    • Abstract

       

      Eight novel silicon-containing diorganotin complexes with salicylaldehyde thiosemicarbazone were synthesized. They were characterized by 1H NMR, 13C NMR, IR spectra, elemental analysis and X-ray singlecrystal diffraction. Spectroscopic and X-rays studies indicated that the thiosemicarbazone Schiff base and tin atom were coordinated as a parallel five- and six-membered heterocyclic structure. In addition, the bioassay of the synthesized complexeswas performed and the results showthat the silicon-containing diorganotin complexeswith salicylaldehyde thiosemicarbazone have good anticancer activity on human breast cancer cells.

    • Author Affiliations

       

      QIAN LIU BO XIE SEN LIN1 QIHUA LIAO RUIHONG DENG YAN ZHAOHUA1

      1. Department of Chemistry, Nanchang University, Nanchang 330031, People’s Republic of China

    • Dates

       
      Published
      August 2019
      Manuscript received
      8 March 2019
      Manuscript revised
      13 May 2019
      Accepted
      24 May 2019

    • Supplementary Material

       

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