Eight novel silicon-containing diorganotin complexes with salicylaldehyde thiosemicarbazone were synthesized. They were characterized by 1H NMR, 13C NMR, IR spectra, elemental analysis and X-ray singlecrystal diffraction. Spectroscopic and X-rays studies indicated that the thiosemicarbazone Schiff base and tin atom were coordinated as a parallel five- and six-membered heterocyclic structure. In addition, the bioassay of the synthesized complexeswas performed and the results showthat the silicon-containing diorganotin complexeswith salicylaldehyde thiosemicarbazone have good anticancer activity on human breast cancer cells.
Volume 135, 2023
Continuous Article Publishing mode
Click here for Editorial Note on CAP Mode