• New self-assembled archetypes in crown ether substituted ∆ZPhe containing tripeptides

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    • Keywords


      Crown ethers peptides; dehydrophenylalanine peptides; self-assembly; metal binding peptides

    • Abstract


      We examine the effect of crown ether ring sizes on structure and properties of three terminally protected tripeptides containing substituted dehydrophenylalanine residues; Bz-∆Phe(12-crown-4)-Phe-Phe-OMe, Bz-∆Phe(15-crown-5)-Phe-Phe-OMe, Bz-∆Phe(18-crown-6)-Phe-Phe-OMe. The resultant self-assembly of the peptides generates nano-vesicles, which further alter into the necklace type of structures that were characterized via their SEM, LRTEM, and AFM images.We also report the disruption of these vesicles in the presence of different metal ions.

    • Author Affiliations



      1. Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh 208016, India
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  • Journal of Chemical Sciences | News

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