An efﬁcient synthesis of a series of pyrazolopyridocoumarins is reported by condensation of 4hydroxycoumarin, benzaldehydes and 1-alkyl-5-amino-pyrazoles in the presence of 10 mol% zinc chloride in ethanol under reﬂux conditions through one-pot reaction. The signiﬁcant attraction of this protocol is being a simple procedure, mild reaction condition, and excellent yield. The molecular structure of the compound (4e) is established by single crystal X-ray structure determination.
Volume 134, 2022
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