1. Home
    2. Journals
    3. Journal of Chemical Sciences
    4. Volume 131
    5. Issue 4

    • Sequential Michael addition/retro-Claisen condensation of 1,3-diarylpropan-1,3-diones with nitrostyrenes: one-step synthesis of 4-nitro-1,3-diarylbutan-1-ones

      ZHENG LI HAO LU ZHENRONG LIU XIAOLONG MA

      Volume 131 Issue 4 April 2019 Article ID 0026

    • Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/131/04/0026

    • Keywords

       

      Michael addition; retro-Claisen condensation; γ-nitro ketone; carbon-carbon bond formation; carbon-carbon bond cleavage

    • Abstract

       

      The sequential Michael addition/retro-Claisen condensation of 1,3-diarylpropan-1,3-diones with nitrostyrenes is described. 4-Nitro-1,3-diarylbutan-1-ones were efficiently synthesized in good to high yield under mild, transition-metal-free condition. This one-step method involving sequential carbon-carbon bond formation and cleavage provides a good alternative to the synthesis of various γ-nitro ketones.

    • Author Affiliations

       

      ZHENG LI1 HAO LU ZHENRONG LIU XIAOLONG MA

      1. College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, Gansu, People’s Republic of China

    • Dates

       
      Published
      April 2019
      Manuscript received
      26 November 2018
      Manuscript revised
      24 January 2019
      Accepted
      5 February 2019

    • Supplementary Material

       

  • Journal of Chemical Sciences | News

© 2023-2024 Indian Academy of Sciences, Bengaluru.

Contact | Site index