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    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/130/06/0073

    • Keywords

       

      Heterocycles; quinolines; transition-metal catalyst; synthetic protocols; biological activities.

    • Abstract

       

      Quinoline is one of the important class of heterocyclic compounds which have gained considerable importance because of its high pharmaceutical efficacy and broad range of biological activities such as anticancer, anti-malarial, anti-microbial and anti-asthmatic. As a consequence, the desire for new versatile andefficient route for the synthesis of quinoline scaffolds remains an active and growing area of interest both in academia and industry. However, developments of transition-metal catalyzed synthetic methods have witnessed a dominant position over the past few years for the synthesis of diverse range of complex heterocyclics containing quinoline scaffolds. This review specifically provides an overview of the literature available on the transition–metal catalyzed synthetic methodologies for the synthesis of polysubstituted quinoline derivatives.

    • Author Affiliations

       

      RASHMI SHARMA PARTEEK KOUR ANIL KUMAR1

      1. Synthetic Organic Chemistry Lab., Faculty of Sciences, Shri Mata Vaishno Devi University, Katra, Jammu and Kashmir 182 320, India

    • Dates

       
      Published
      June 2018
      Manuscript received
      22 January 2018
      Manuscript revised
      26 March 2018
      Accepted
      27 March 2018

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