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    • Catalyst-free aldol reaction of N-substituted rhodanines on aqueous media

      N S DEVI NIRADA DEVI

      Volume 130 Issue 2 February 2018 Article ID 0018

    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/130/02/0018

    • Keywords

       

      Rhodanines; aldol reaction; green chemistry; catalyst-free; heterocycles.

    • Abstract

       

      Rhodanine derivatives are highly valuable heterocycles in drug discovery. Here, we developed aldol reaction of N-substituted rhodanines and aromatic aldehydes on water. The reaction was performed at room temperature affording the products in good to high yield. This synthetic protocol uses simple experimental procedures, catalyst-free, and avoids the use of highly toxic solvents.

    • Author Affiliations

       

      N S DEVI NIRADA DEVI1

      1. Department of Chemistry, Cotton University, Guwahati, Assam 781 001, India

    • Dates

       
      Published
      February 2018
      Manuscript received
      1 October 2017
      Manuscript revised
      24 November 2017
      Accepted
      22 December 2017

    • Supplementary Material

       

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