• Catalyst-free aldol reaction of N-substituted rhodanines on aqueous media

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      https://www.ias.ac.in/article/fulltext/jcsc/130/02/0018

    • Keywords

       

      Rhodanines; aldol reaction; green chemistry; catalyst-free; heterocycles.

    • Abstract

       

      Rhodanine derivatives are highly valuable heterocycles in drug discovery. Here, we developed aldol reaction of N-substituted rhodanines and aromatic aldehydes on water. The reaction was performed at room temperature affording the products in good to high yield. This synthetic protocol uses simple experimental procedures, catalyst-free, and avoids the use of highly toxic solvents.

    • Author Affiliations

       

      N S DEVI NIRADA DEVI1

      1. Department of Chemistry, Cotton University, Guwahati, Assam 781 001, India
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    • Supplementary Material

       
  • Journal of Chemical Sciences | News

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