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      https://www.ias.ac.in/article/fulltext/jcsc/129/04/0415-0420

    • Keywords

       

      Ritter reaction; sulfated polyborate; N-tert-butyl amide; solvent-free condition.

    • Abstract

       

      Rapid, efficient and inexpensive method for synthesis of N-tert-butyl/N-trityl protected amides via Ritter reaction of nitriles with tertiary alcohols in the presence of a sulfated polyborate catalyst under solvent-free conditions is described. The catalyst has the advantage of Lewis as well as Bronsted acidity and recyclability without significant loss in catalytic activity along with easy work-up, short reaction time and good to excellent yields.

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  • Journal of Chemical Sciences | News

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