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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/129/03/0329-0333

    • Keywords

       

      Alicyclic fused pyrimidone; aminoacrylates; lactams; phosphorus oxychloride; cyclisation.

    • Abstract

       

      A facile and versatile method for the synthesis of alicyclic fused pyrimidones from aminoacrylates and lactams in the presence of phosphorous oxychloride is described. The results suggest that this method is widely applicable except for cyclobutyl fused systems. This method gives better yield than the method ofcondensing aminopyrrolidines with the beta keto esters.

    • Author Affiliations

       

      SAMIKANNU RAMESH1 PON SARAVANAKUMAR1 RAMASAMY DURAISAMY1 ARVIND MATHUR2 PIRAMA NAYAGAM ARUNACHALAM1

      1. Biocon Bristol-Myers Squibb Research Center, Syngene International Pvt. Ltd., Biocon Park, Plot No. 2 &3, Bommasandra–Jigani Road, Bangalore 560 100, India
      2. Research and Development, Bristol-Myers Squibb, P.O. Box 5400, Princeton, New Jersey 08543, USA
    • Dates

       
    • Supplementary Material

       
  • Journal of Chemical Sciences | News

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