1,2,3-Triazole N(2)-coordinated C-O coupling: Access to ortho aryloxyl 1,4-diaryl 1,2,3-triazoles
YAOWEN LIU FEN ZHAO HAOHUA ZHOU KAI XIE YUBO JIANG
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CuI-catalyzed selective Ullmann C–O coupling of 1,4-disubstituted 1,2,3-triazole bromides with phenols were achieved through the coordination of N(2) atom. The ortho C–Br bond in N(1) aryl can be selectively coupled with phenols, while other C–Br bonds remain inert, generating ortho aryloxyl 1,4-diaryl1,2,3-triazoles.
Volume 135, 2023
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