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    5. Issue 11

    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/128/11/1789-1794

    • Keywords

       

      1,2-Diacetyl D-erythro-sphinganine; 1,2-diacetyl L-threo-sphinganine; D-erythro-sphinganine triacetate; sphingolipids; total synthesis; Garner aldehyde.

    • Abstract

       

      A novel sphingosine, 1,2-diacetyl D-erythro-sphinganine having a characteristic almond flavour was isolated from the edible mushroom Grifola gargal. We have synthesized this sphinganine along with the three other sphingolipids, such as 1,2-diacetyl L-threo-sphinganine, D-erythro-sphinganine triacetateand L-threo-sphinganine triacetate using Garner aldehyde as the starting material involving the Grignard reaction and Mitsunobu inversion. The sphingolipids 1,2-diacetyl D-erythro-sphinganine and 1,2-diacetyl L-threo-sphinganine have been synthesized for the first time.

    • Author Affiliations

       

      PARAMESH JANGILI PERLA RAMESH BISWANATH DAS

      1. Dates

         
        Published
        2 November 2016
        Manuscript received
        13 July 2016
        Manuscript revised
        9 September 2016
        Accepted
        9 September 2016

      2. Supplementary Material

         

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