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      https://www.ias.ac.in/article/fulltext/jcsc/128/11/1775-1782

    • Keywords

       

      Copper; X-ray structure; radical activity; catechol oxidase activity

    • Abstract

       

      An unprecedented solid of coper(II) complexes [Cu(dpa)₂NCS]₂[Cu(dpa)₂(NCS)₂](ClO₄)₂ (1) [dpa = 2,2'-dipyridylamine; SCN = thiocyanate], has been synthesized and crystallographically characterized with the aim to study the catecholase activity. The Cu(II) complex mimics the full catalytic cycle of the active site of catechol oxidase enzyme in acetonitrile medium with a turnover number of 4.788 × 10³ h⁻¹ along with the production of semiquinone radical and hydrogen peroxide. In situ generation of Cu(I) species in the catalytic pathway of catechol oxidation was established by electrochemical study and further confirmed by electron paramagnetic resonance (EPR) spectroscopy.

    • Author Affiliations

       

      ABHRANIL DE1 DHANANJAY DEY1 HARE RAM YADAV2 MILAN MAJI3 VINAYAK RANE4 R M KADAM4 ANGSHUMAN ROY CHOUDHURY2 BHASKAR BISWAS1

      1. Department of Chemistry, Raghunathpur College, Purulia, West Bengal, 723 133 India
      2. Department of Chemical Sciences, Indian Institute of Science Education and Research Mohali, Sector 81, S A S Nagar, Manauli P. O. Mohali, Punjab, 140 306, India
      3. Department of Chemistry, National Institute of Technology, Mahatma Gandhi Avenue, Durgapur, West Bengal, 713 209, India
      4. Radiochemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai, Maharashtra 400 085, India
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    • Supplementary Material

       
  • Journal of Chemical Sciences | News

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