Synthesis and anti-acetylcholinesterase activity of benzotriazinone-triazole systems
SETAREH MOGHIMI FERESHTEH GOLI-GARMROODI HEDIEH PILALI MOHAMMAD MAHDAVI LOGHMAN FIROOZPOUR HAMID NADRI ALIREZA MORADI ALI ASADIPOUR ABBAS SHAFIEE ALIREZA FOROUMADI
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An approach for the construction of benzotriazinone-triazole system is described. The synthesis is based on diazonium chemistry and subsequent intramolecular heteroatom-heteroatom bond formation. The introduction of triazole moiety occurred via click reaction catalyzed by nano-sized copper, supported on modified silica mesopore KIT-5 leading to the desired products in excellent yield. Also, in vitro acetylcholinesterase(AChE) inhibitory activities of the target compounds were screened by Ellman’s method.
SETAREH MOGHIMI1 FERESHTEH GOLI-GARMROODI1 HEDIEH PILALI1 MOHAMMAD MAHDAVI2 LOGHMAN FIROOZPOUR2 HAMID NADRI3 ALIREZA MORADI3 ALI ASADIPOUR4 ABBAS SHAFIEE1 ALIREZA FOROUMADI1 2
Volume 135, 2023
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