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    5. Issue 8

    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/128/08/1321-1325

    • Keywords

       

      Oxidation; sulfide; sulfoxide; sulfone; benzimidazole anthelmintic

    • Abstract

       

      An improved green route has been developed for the oxidation of sulfide compounds. Albendazole is converted to ricobendazole or albendazole sulfone using H₂O₂ as an oxidant and H₂O as the solvent. High yields of the corresponding products were obtained by carrying out the reaction at room temperature. This synthetic method is environmentally clean and safe, operationally simple for the oxidation of other benzimidazole anthelmintics and various sulfide compounds.

    • Author Affiliations

       

      RAVINDRA B WAGH SITARAM H GUND JAYASHREE M NAGARKAR

      1. Dates

         
        Published
        1 August 2016
        Manuscript received
        22 March 2016
        Manuscript revised
        11 May 2016
        Accepted
        24 May 2016

      2. Supplementary Material

         

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