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Fe& #8323; O& #8324; /AO/Pd; magnetic nanoparticles; heterogeneous catalyst; Pd nanoparticles; suzuki; ullmann.

The Pd supported on amidoxime (AO)-functionalized Fe₃O₄ ( Fe₃O₄ /AO/Pd) hybrid material was used as an effective and recyclable nanocatalyst in Suzuki-Miyaura coupling reactions. The catalyst was very effective for the Suzuki-Miyaura reaction of aryl halides (Ar–I, Ar–Br, Ar–Cl) with phenylboronic acid and conversion was excellent in most cases. The yields of the products were in the range from 7–98%. The catalyst showed good stability and could be recovered and reused for six reaction cycles without a significant loss in its catalytic activity. Also, a wide range of N-arylated indoles are selectively synthesized through inter molecular C(aryl)–N bond formation from the corresponding aryl iodides and indoles through Ullmann-type coupling reactions in the presence of the prepared catalyst.

RAMIN GHORBANI-VAGHEI¹ SABA HEMMATI¹ MALAK HEKMATI²

1. Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, 6517838683 Hamedan, Iran
2. Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Chemistry, Pharmaceutical Sciences Branch, (IAUPS), Tehran, Iran

Published

1 July 2016

Manuscript received

21 January 2016

Manuscript revised

3 April 2016

Accepted

30 April 2016