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      https://www.ias.ac.in/article/fulltext/jcsc/128/04/0562-0572

    • Keywords

       

      Bischler–Napieralski reaction; tetrahydro-& #x0392; -carboline; ketene S,S–acetals; In $Cl_{3}$; one-pot

    • Abstract

       

      A novel and facile one-pot synthesis of 1-substituted tetrahydro-Β-carbolines by cyclocondensationof ketene S,S–acetals with tryptamine in presence of In $Cl_{3}$ and TFA as co-catalysts by Bischler-Napieralskicyclization is described. The reaction involves formation of one C-N bond, one C-C bond and a new ringannulation over an indole moiety.

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    • Dates

       
  • Journal of Chemical Sciences | News

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      Posted on July 25, 2019

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