• Mn(II) complexes with bipyridine, phenanthroline and benzoic acid: Biological and catalase-like activity

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    • Keywords


      Manganese complex; catalase; biological activity; hydrogen peroxide; bipyridine; phenanthroline

    • Abstract


      Five mononuclear Mn(II) complexes, [Mn(phen)²(ClO´)²] (1), [Mn(phen)³](ClO´)²(H²CO³)²(2),

      [Mn(bipy)²(ClO´)²] (3), [Mn(bipy)³](ClO´)²) (4), and Mn(phen)²(ba)(H²O)](ClO´)(CH³OH) (5), where bipy

      = 2,2’-bipyridine, phen = 1,10-phenanthroline, and ba = benzoic acid were prepared and characterized by Xray,IR and UV-Vis spectroscopies, and their catalase-like and biological activities were studied. The presenceof two different types and the number of chelating NN-donor neutral ligands allowed for analysis of theireffects on the catalase and biological activities. It was observed that the presence and number of phen ligandsimproved the activity more than the bipy ligand. Complexes 1 and 2, which contain more basic phen ligands,disproportionate H²O² faster than complexes 3 and 4, which contain less basic bipy ligands. The in vitroantimicrobial activities of all the complexes were also tested against seven bacterial strains by microdilutiontests. All the bacterial isolates demonstrated sensitivity to the complexes and the antifungal (anticandidal)activities of the Mn(II) complexes were remarkably higher than the reference drug ketoconazole

    • Author Affiliations



      1. aDepartment of Chemistry, Faculty of Sciences, Anadolu University, Eskişehir, Turkey
      2. bDepartment of Biology, Faculty of Sciences, Anadolu University, Eskişehir, Turkey
    • Dates

  • Journal of Chemical Sciences | News

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