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    • Keywords


      Multi component reaction; cyclocondensation; 1-thiocarbamidoalkyl-2-naphthols; acetylenic esters; thiazolidin-4-ones

    • Abstract


      This investigation was set to provide derivatives of thiazolidin-4-ones incorporated with amino-alkyl naphthols in a molecular frame work. For this purpose, a series of 1-thiocarbamidoalkyl-2-naphthols was prepared by the three component condensation of aromatic aldehydes, phenylthiourea and 2-naphthol. In the next step, these compounds underwent reaction with dialkyl acetylenedicarboxylates at ambient temperature in ethanol to afford the corresponding 4-thiazolidinones in high yields. Following the completion of the reaction, the products were solidified and isolated by filtration. The method is easy, inexpensive, chemoselective and environmentally benign and illustrates an interesting instance of click chemistry.

    • Author Affiliations


      Sakineh Amini1 Ahmad Momeni Tikdari1 Hojatollah Khabazzadeh1

      1. Department of Chemistry, Shahid Bahonar University of Kerman, Kerman 7616914111, Iran
    • Dates

  • Journal of Chemical Sciences | News

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