• Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/127/10/1739-1746

    • Keywords

       

      Isothiocyanates; Isocyanates; 6-Fluoro-3-(piperidin-4-yl)benzo[𝑑] isoxazole; Antimicrobial and Antioxidant activity.

    • Abstract

       

      A new class of antimicrobial and antioxidant agents, based on thiourea and urea derivatives of 6-fluoro-3-(piperidin-4-yl)benzo[𝑑] isoxazole were synthesized by adopting a simple and efficient method. Synthesized compounds were characterized by spectral data of IR, $^{1}_{}$H, $^{13}_{}$C NMR and mass spectra. The compounds were evaluated for their efficacy as antimicrobial and antioxidant agents. A few compounds showed good antibacterial, antifungal and antioxidant activity when compared to standard drugs and thus represent a new class of promising lead compounds.

    • Author Affiliations

       

      Hasti Sudhamani1 S K Thaslim Basha1 Nagam Venkateswarlu2 Tartte Vijaya2 Chamarthi Nagaraju1

      1. Department of Chemistry, S V University, Tirupati 517 502, Andhra Pradesh, India
      2. Department of Botany, S V University, Tirupati 517 502, Andhra Pradesh, India
    • Dates

       
  • Journal of Chemical Sciences | News

© 2021-2022 Indian Academy of Sciences, Bengaluru.