• Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/127/08/1405-1410

    • Keywords

       

      𝛽-Bromo-tert-alcohols; microwave; bi-functional activation; ZnS; flavour compounds.

    • Abstract

       

      Microwave-assisted dehydration-oxidation of 𝛽-bromo-tert-alcohols to afford 2,3-unsaturated ketones in good yield is reported. The reaction of substrates with DMSO in 1:1 ratio (w/v) is promoted by ZnS in a solvent-free condition. A concurrent bi-functional activation of trans-vicinal bromo- and hydroxyl groups with ZnS is elucidated. This is a new observation under microwave and applies to 𝛽-bromo-tert-alcohols derived from 1,4-disubstitued-1-cyclohexenes. It is very useful in the synthesis of 2,3-unsaturated ketones derived from monoterpenes which are valuable flavour compounds.

    • Author Affiliations

       

      Nandini Kannan1 Manjunatha Javagal Rangaswamy1 Bettadaiah Bheemanakere Kemapaiah1

      1. Spice and Flavour Science Department, CSIR-Central Food Technological Research Institute, Mysore 570 020, India
    • Dates

       
    • Supplementary Material

       
  • Journal of Chemical Sciences | News

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2017-2019 Indian Academy of Sciences, Bengaluru.