• Fulltext


        Click here to view fulltext PDF

      Permanent link:

    • Keywords


      𝛽-Bromo-tert-alcohols; microwave; bi-functional activation; ZnS; flavour compounds.

    • Abstract


      Microwave-assisted dehydration-oxidation of 𝛽-bromo-tert-alcohols to afford 2,3-unsaturated ketones in good yield is reported. The reaction of substrates with DMSO in 1:1 ratio (w/v) is promoted by ZnS in a solvent-free condition. A concurrent bi-functional activation of trans-vicinal bromo- and hydroxyl groups with ZnS is elucidated. This is a new observation under microwave and applies to 𝛽-bromo-tert-alcohols derived from 1,4-disubstitued-1-cyclohexenes. It is very useful in the synthesis of 2,3-unsaturated ketones derived from monoterpenes which are valuable flavour compounds.

    • Author Affiliations


      Nandini Kannan1 Manjunatha Javagal Rangaswamy1 Bettadaiah Bheemanakere Kemapaiah1

      1. Spice and Flavour Science Department, CSIR-Central Food Technological Research Institute, Mysore 570 020, India
    • Dates

    • Supplementary Material

  • Journal of Chemical Sciences | News

© 2021-2022 Indian Academy of Sciences, Bengaluru.