SiO2-Diphenic acid: An efficient and recyclable heterogeneous catalyst for one-pot synthesis of bis-(indolyl)methane derivatives in liquid phase
R Vaid M Gupta O S Chambyal R Gupta
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An eco-friendly and expedient procedure for one-pot synthesis of is-(indolyl)methane derivatives via electrophilic substitution reaction at C-3 position of indole with various aldehydes has been developed by using silica-diphenic acid as a novel heterogeneous catalyst. This method has various promising features such as short reaction time, easy work-up procedure, good yield of products and remarkable activity and selectivity of the catalyst.
R Vaid1 M Gupta1 O S Chambyal1 R Gupta1
Volume 135, 2023
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