1. Home
    2. Journals
    3. Journal of Chemical Sciences
    4. Volume 127
    5. Issue 5

    • Nano-TiCl4/SiO2: An efficient heterogeneous solid acid catalyst for the one pot cascade five-component synthesis of densely functionalized tetrahydropyridines

      Abdolhamid Bamoniri Bi Bi Fatemeh Mirjalili Reza Tarazian

      Regular Articles Volume 127 Issue 5 May 2015 pp 885-895

    • Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/127/05/0885-0895

    • Keywords

       

      Tetrahydropyridines; Nano-TiCl4/SiO2; heterogeneous catalyst; five-component reaction; onepot synthesis.

    • Abstract

       

      Nano-TiCl4/SiO2 was found to be an inexpensive and efficient heterogeneous solid acid catalyst for the synthesis of one-pot cascade synthesis of highly functionalized asymmetric tetrahydropyridines from the five-component condensation reaction of the para-substituted anilines and aromatic aldehydes with ethyl acetoacetate under thermal conditions. Novel methodology, environmentally benign conditions, clean protocol, easy work-up and high yields are the important advantages of this protocol. The products were characterized using physical and spectroscopic data such as FT-IR, 1H-NMR and in some cases 13C-NMR and CHN analysis.

    • Author Affiliations

       

      Abdolhamid Bamoniri1 Bi Bi Fatemeh Mirjalili2 Reza Tarazian1

      1. Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, I.R. Iran
      2. Department of Chemistry, College of Science, Yazd University, Yazd, I. R. Iran

    • Dates

       
      Published
      May 2015
      Manuscript received
      8 May 2014
      Manuscript revised
      31 October 2014
      Accepted
      23 December 2014

    • Supplementary Material

       

  • Journal of Chemical Sciences | News

© 2022-2023 Indian Academy of Sciences, Bengaluru.

Contact | Site index