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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/126/05/1275-1284

    • Keywords

       

      Imidazolin-5-one; gfp chromophore; C-H$\ldots \pi$ stacking; hydrogen bonding; photophysical study.

    • Abstract

       

      Crystal structures of four green fluorescent protein (GFP) chromophore analogues with different packing interactions could be tuned by appropriate substitutions around the imidazolin-5-one ring are reported here. Compound 1 was crystallized from tetrahydrofuran at room temperature while compounds 2-4 have been crystallized from a mixture of methanol and dichloromethane in 3:1 ratio. Molecule 1, 2 and 3 crystallized in monoclinic lattice while molecule 4 preferred to crystallize in a triclinic crystal system. The crystal packing of these molecules was stabilized by C-H$\ldots \pi$ stacking and C-H$\ldots $O type of supramolecular interactions. The results reveal that packing diversity can be easily accomplished in these molecules by tuning the substituents around the imidazolin-5-one ring. Photophysical studies also reveal that all have good quantum yield and fluoresce typically in red region due to presence of electron donating groups around the imidazolin-5-one ring.

    • Author Affiliations

       

      Ashish Singh1 Basanta Kumar Rajbongshi1 Gurunath Ramanathan1

      1. Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208 016, India
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    • Supplementary Material

       
  • Journal of Chemical Sciences | News

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