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Nerve agents; oximes; hydrogen bond; organophosphate stimulant.

In this contribution, the ability of simple oximes to bind a well-known nerve agent simulant (dimethylmethylphosphonate, DMMP) via hydrogen bond is reported. UV/Vis measurements indicate the formation of 1:1 complexes. ¹H-, ³¹P-NMR titrations and T-ROESY experiments confirm that oximes bind the organophosphate via hydrogen bond.

Andrea Pappalardo¹ Maria E Amato¹ Francesco P Ballistreri¹ Valentina La Paglia Fragola¹ Gaetano A Tomaselli¹ Rosa Maria Toscano¹ Giuseppe Trusso Sfrazzetto¹

1. Dipartimento di Scienze Chimiche, Università di Catania, viale A Doria 6, 95125 Catania, Italy

Manuscript received

17 December 2012

Manuscript revised

1 March 2013

Accepted

5 April 2013

• supp21.pdf