Phenylboronic acid catalysed synthesis of 1,5-benzodiazepines via cyclocondensation of 𝑜-phenylenediamine and ketones
Santosh V Goswami Prashant B Thorat Sudhakar R Bhusare
Click here to view fulltext PDF
Phenylboronic acid has been found to be an efficient catalyst for the synthesis of 1,5-benzodiazepine derivatives via cyclocondensation of 𝑜-phenylenediamine and various ketones in good to excellent yields (82-91%) using acetonitrile as solvent at reflux condition. The remarkable advantages offered by this method are easy mild reaction condition, experimental work up and good to excellent yields of products.
Santosh V Goswami1 Prashant B Thorat1 Sudhakar R Bhusare1
Volume 135, 2023
Continuous Article Publishing mode
Click here for Editorial Note on CAP Mode