1. Home
    2. Journals
    3. Journal of Chemical Sciences
    4. Volume 125
    5. Issue 4

    • Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/125/04/0745-0749

    • Keywords

       

      Phenylboronic acid; o-phenylenediamine; ketones; 1,5-benzodiazepines.

    • Abstract

       

      Phenylboronic acid has been found to be an efficient catalyst for the synthesis of 1,5-benzodiazepine derivatives via cyclocondensation of 𝑜-phenylenediamine and various ketones in good to excellent yields (82-91%) using acetonitrile as solvent at reflux condition. The remarkable advantages offered by this method are easy mild reaction condition, experimental work up and good to excellent yields of products.

    • Author Affiliations

       

      Santosh V Goswami1 Prashant B Thorat1 Sudhakar R Bhusare1

      1. Department of Chemistry, Dnyanopasak College, Parbhani 431 401, India

    • Dates

       
      Published
      July 2013
      Manuscript received
      28 November 2012
      Manuscript revised
      27 January 2013
      Accepted
      1 March 2013

  • Journal of Chemical Sciences | News

© 2022-2023 Indian Academy of Sciences, Bengaluru.

Contact | Site index