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    • Keywords


      Cannizzaro reaction; bromocyclisation; 2-methoxy-3-formylquinolines; furoquinolines; 2-chloro-3-formylquinolines.

    • Abstract


      Cannizzaro reaction of 2-chloro-3-formylquinolines was investigated under two different conditions. Under both conditions, redox and methoxylation proceeded simultaneously and gave 2-methoxy- 3-formylquinolines, 2-methoxyquinolin-3-yl-methanols and 2-methoxyquinoline-3-carboxylic acids. The synthesized 2-methoxy-3-formylquinolines were then condensed with acetone in the presence of sulphuric acid to give 4-(2-methoxy-quinolin-3-yl)-but-3-en-2-ones which in turn were bromocyclized and dehydrobrominated to get 2-acetylfuro[2,3-𝑏]quinolines.

    • Author Affiliations


      Devadoss Karthik Kumar1 Rajakandhan Shankar1 Subramaniam Parameswaran Rajendran1

      1. Department of Chemistry, School of Chemical Sciences, Bharathiar University, Coimbatore 641 046, India
    • Dates

  • Journal of Chemical Sciences | News

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