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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/124/05/1019-1023

    • Keywords

       

      2-(4-(2-Morpholinoethoxy)phenyl)-N-phenylacetamides; in vitro antimicrobial activity; heterocycles; clotrimazole.

    • Abstract

       

      A new class of potential biologically active 2-(4-(2-morpholinoethoxy)phenyl)-N-phenylacetamides has been synthesized from hydroxyphenylacetic acid. The products were characterized through IR, 1H NMR, mass spectral studies and elemental analysis. The compounds were screened for antimicrobial activity by disc agar diffusion technique. The potency of compounds is tested against variety of fungal and bacterial strains in comparison to clotrimazole and streptomycin, respectively. Some of the synthesized compounds exhibit superior in vitro activity compared to the standard drugs.

    • Author Affiliations

       

      H P Jayadevappa1 G Nagendrappa1 S Umesh2 S Chandrashekar2

      1. Department of Studies in Chemistry, Manasagangotri, Mysore 570 006, India
      2. Department of Studies in Applied Botany and Biotechnology, Manasagangotri, Mysore 570 006, India
    • Dates

       
  • Journal of Chemical Sciences | News

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