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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/124/05/1013-1017

    • Keywords

       

      Pyranopyrazoles; solvent-free synthesis; multicomponent reaction; ionic liquid; heterogeneous catalysts.

    • Abstract

       

      A simple, green and efficient protocol for synthesis of dihydropyrano[2,3-c]pyrazole derivatives is developed by a four component reaction of various benzaldehydes, ethyl acetoacetate, hydrazine hydrate and malononitrile in the presence of 3-methyl-1-(4-sulphonic acid)butylimidazolium hydrogen sulphate [(CH2)4SO3HMIM][HSO4], an acidic ionic liquid and as a catalyst, under solvent-free conditions. The key advantages of this process are high yields, shorter reaction times, easy work-up, purification of products by non-chromatographic method and the reusability of the catalyst.

    • Author Affiliations

       

      Javad Ebrahimi1 Ali Mohammadi2 Vahid Pakjoo3 Esan Bahramzade4 Amir Habibi3

      1. Young Researchers Club, Islamic Azad University, Mashhad Branch, P.O. Box 9187147578, Mashhad, Iran
      2. Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, P.O. Box 91775, Mashhad, Iran
      3. Department of Chemistry, Islamic Azad University, Mashhad Branch, P.O. Box 9187147578, Mashhad, Iran
      4. Department of Chemistry, Islamic Azad University, Mashhad Branch, P.O. Box 9187147578, Mashhad, Iranv
    • Dates

       
  • Journal of Chemical Sciences | News

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