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    • Keywords


      Microwave; one-pot synthesis; benzothiazoles; benzoxazoles; analgesic activity.

    • Abstract


      Microwave-assisted synthesis of benzothiazole and benzoxazole libraries via PIFA promoted cyclocondensation of 2-aminothiophenols/2-aminophenols with aldehydes under one-pot condition in good to excellent yields was achieved. Twenty compounds have been investigated for their analgesic activity and showed moderate to good activity.

    • Author Affiliations


      C Praveen1 A Nandakumar1 P Dheenkumar2 D Muralidharan1 P T Perumal1

      1. Organic Chemistry Division, Central Leather Research Institute (CSIR), Adyar, Chennai 600 020, India
      2. Department of Pharmaceutical Chemistry, EGS Pillay College of Pharmacy, Nagapattinam 611 002, India
    • Dates

    • Supplementary Material

  • Journal of Chemical Sciences | News

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      Posted on July 25, 2019

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