Click here to view fulltext PDF

Permanent link:
https://www.ias.ac.in/article/fulltext/jcsc/123/06/0937-0942

Palladium; terminal alkynes; benzotriazole; amine-free; copper-free.

An efficient Pd-catalysed Sonogashira coupling reaction was achieved in the absence of copper and amine with inorganic base using phosphene-free, air stable di(1𝐻-benzo[𝑑][1,2,3]triazol-1-yl)methane as ligand. The cross coupling of electron-rich, electron-defficient and hindered aryl halides with terminal alkynes afforded the internal alkynes in good to excellent yields.

Jaspal Singh¹ Akhilesh Kumar Verma¹

1. Synthetic Organic Chemistry Research Laboratory, Department of Chemistry, University of Delhi, Delhi 110007, India

Published

November 2011

• 20Supporting Information R1