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    • Keywords


      Tetrazoles; ZrOCl2·8 H2O; DMF; arylnitriles; sodium azide.

    • Abstract


      A simple, efficient and a versatile method for the synthesis of 5-substituted-1𝐻-tetrazoles by a [3+2]-cycloaddition reaction of arylnitriles with sodium azide in DMF using ZrOCl2·8 H2O as catalyst has been developed. The reactions work well at 100°C and give the desired products in excellent yield. The examples studied include arylnitriles having electron donating as well as electron releasing groups on the arene nucleus.

    • Author Affiliations


      Madhusudana Reddy Muthukur Bhoje Gowd1 Mohamed Afzal Pasha1

      1. Department of Studies in Chemistry, Central College Campus, Bangalore University, Bangalore 560 001, India
    • Dates

  • Journal of Chemical Sciences | News

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