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    • Keywords


      Multi component reaction; 3-cyanoacetyl indole; malononitrile; pyridine synthesis; antiinflammatory activity; analgesic activity.

    • Abstract


      A simple protocol for the efficient preparation of 2-($1H$-Indol-3-yl)-6-methoxy-4-arylpyridine-3,5-dicarbonitrile has been achieved through one-pot multi-component reaction under reflux condition. These compounds showed a good anti-inflammatory activity. Also a series of bis-Hantzsch dihydropyridine derivatives were synthesized and they exhibit analgesic activity.

    • Author Affiliations


      Prakasam Thirumurugan1 S Mahalaxmi1 Paramasivan T Perumal1

      1. Organic Chemistry Division, Central Leather Research Institute, Adyar, Chennai 600 020
    • Dates

  • Journal of Chemical Sciences | News

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