• Towards chiral diamines as chiral catalytic precursors for the borane-mediated enantioselective reduction of prochiral ketones

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    • Keywords


      ($3S$)-3-Anilinomethyl-1,2,3,4-tetrahydroisoquinoline; ($2R$)-2-anilinomethylpiperidine; (𝑆)-phenylalanine; asymmetric reduction.

    • Abstract


      Two chiral diamines ($3S$)-3-anilinomethyl-1,2,3,4-tetrahydroisoquinoline (1) and ($2R$)-2-anilinomethylpiperidine (2) have been employed as chiral catalytic sources in the borane-mediated asymmetric reduction of prochiral ketones thus providing the resulting secondary alcohols in good enantiomeric purities (up to 81% $ee$).

    • Author Affiliations


      Deevi Basavaiah1 Utpal Das1 Suparna Roy1

      1. School of Chemistry, University of Hyderabad, Hyderabad 500 046
    • Dates

  • Journal of Chemical Sciences | News

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