• Chemoselective reaction of cyanoacetic acid with benzal-4-acetylanilines and fungitoxicity of products

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/121/04/0449-0453

    • Keywords

       

      4-Aminoacetophenone; cyanoacetic acid; benzal-4-acetylanilines; benzalcyanoacetic acid; fungitoxicity.

    • Abstract

       

      Cyanoacetic acid reacted chemoselectively with carbon-nitrogen double bond of benzal-4-acetylaniliines, leaving the carbon-oxygen double bond, considered to be more reactive, intact, leading to the formation of mono addition-elimination products rather than bis attack at both the reactive centres, even when the reaction was carried out with two moles of cyanoacetic acid. The product viz. benzalcyanoacetic acid and its derivatives were screened for their fungitoxicity against five pathogenic fungi.

    • Author Affiliations

       

      Anjali Sidhu1 J R Sharma1 Mangat Rai1

      1. Department of Chemistry, Punjab Agricultural University, Ludhiana 141 004
    • Dates

       
  • Journal of Chemical Sciences | News

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