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    • Facilitation of peptide fibre formation by arginine-phosphate/carboxylate interactions

      K Krishna Prasad Sandeep Verma

      Volume 120 Issue 1 January 2008 pp 155-162

    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/120/01/0155-0162

    • Keywords

       

      Peptide; self-assembly; arginine; microscopy.

    • Abstract

       

      This study describes peptide fibre formation in a hexapeptide, derived from the V3 loop of HIV-1, mediated by the interactions between arginine residues and phosphate/carboxylate anions. This charge neutralization approach was further confirmed when the deletion of arginine residue from the hexapeptide sequence resulted in fibre formation, which was studied by a combination of microscopic techniques.

    • Author Affiliations

       

      K Krishna Prasad1 Sandeep Verma1

      1. Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208 016

    • Dates

       
      Published
      January 2008

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