• Facilitation of peptide fibre formation by arginine-phosphate/carboxylate interactions

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    • Keywords


      Peptide; self-assembly; arginine; microscopy.

    • Abstract


      This study describes peptide fibre formation in a hexapeptide, derived from the V3 loop of HIV-1, mediated by the interactions between arginine residues and phosphate/carboxylate anions. This charge neutralization approach was further confirmed when the deletion of arginine residue from the hexapeptide sequence resulted in fibre formation, which was studied by a combination of microscopic techniques.

    • Author Affiliations


      K Krishna Prasad1 Sandeep Verma1

      1. Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208 016
    • Dates

  • Journal of Chemical Sciences | News

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