• Evidence for covalent binding of epicocconone with proteins from synchronous fluorescence spectra and fluorescence lifetimes

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      https://www.ias.ac.in/article/fulltext/jcsc/119/02/0099-0104

    • Keywords

       

      Covalent binding; epicocconone; synchronous fluorescence spectra; fluorescence lifetimes.

    • Abstract

       

      Synchronous fluorescence and time-resolved fluorescence spectroscopic studies that reveal the interaction of epicocconone with human serum albumin is significantly different from its interaction with surfactant assemblies. This observation, along with steady-state fluorescence data, indicates groundstate interaction between the fluorophore epicocconone and the protein. Similarity in fluorescence properties with the adduct of the fluorophore with 𝑛-butylamine indicates that bonding occurs at the Nterminus of the protein.

    • Author Affiliations

       

      Debashis Panda1 Anindya Datta1

      1. Department of Chemistry, Indian Institute of Technology - Bombay, Powai, Mumbai 400 076
    • Dates

       
  • Journal of Chemical Sciences | News

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