• One-pot efficient green synthesis of 1,4-dihydro-quinoxaline-2,3-dione derivatives

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    • Keywords


      Green chemistry; quinoxaline; o-phenylene diamine; oxalic acid; grinding; atom economy

    • Abstract


      An efficient synthesis of the potential pharmacophore 1,4-dihydro-quinoxaline-2,3-dione (1) has been achieved in a one-pot reaction at room temperature from substitutedo-phenylene diamine and oxalic acid under solvent-free conditions by a simple grinding method with unsurpassed atom economy. Thermal and powder X-ray diffraction analysis was carried out for some hydrated crystals.

    • Author Affiliations


      Harjyoti Thakuria1 Gopal Das1

      1. Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati - 781 039
    • Dates

  • Journal of Chemical Sciences | News

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