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    • Keywords


      3d-Metal complexes; thiosemicarbazide; antitumour activity

    • Abstract


      The ligand 1,4-dibenzoyl-3-thiosemicarbazide (DBtsc) forms complexes [M(DBtsc-H)(SCN)] [M = Mn(II), Co(II) or Zn(II)], [M(DBtsc-H) (SCN)(H2O)] [M = Ni(II) or Cu(II)], [M(DBtsc-H)Cl] [M = Co(II), Ni(II), Cu(II) or Zn(II)] and [Mn(DBtsc)Cl2], which have been characterized by elemental analyses, magnetic susceptibility measurements, UV/Vis, IR,1H and13C NMR and FAB mass spectral data. Room temperature ESR spectra of the Mn(II) and Cu(II) complexes yield <g> values, characteristic of tetrahedral and square planar complexes respectively. DBtsc and its soluble complexes have been screened against several bacteria, fungi and tumour cell lines.

    • Author Affiliations


      Nand K Singh1 Saty B Singh1 Anuraag Shrivastav1 Sukh M Singh2

      1. Department of Chemistry, Banaras Hindu University, Varanasi - 221 005, India
      2. School of Biotechnology, Banaras Hindu University, Varanasi - 221 005, India
    • Dates

  • Journal of Chemical Sciences | News

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