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Collagen; collagenase; chromium(III); tanning; stabilisation of collagen

A molecular insight into the mechanism of stabilisation of collagen against the action of collagenase and wet heat leading to tanning has been gained. The variations in the extent of stabilisation of collagen with the nature of the molecular species of chromium(III) have been demonstrated experimentally. A case has been made to conceive tanning as emerging from an increase in long-range order and chromium(III)-induced molecular assembly of collagen.

R Gayatri¹ Rama Rajaram¹ Balachandran Unni Nair¹ F Chandrasekaran¹ T Ramasami¹

1. Central Leather Research Institute, Adyar, Chennai - 600 020, India

Published

February 1999