• Equilibrium studies of binary and ternary complexes of oxytetracycline and amino acid or DNA units

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    • Keywords


      Oxytetracycline; acid-dissociation constants; binary and ternary complexes

    • Abstract


      The acid-dissociation constants of oxytetracycline (OTC) and the formation constants of the copper(II) complexes were determined att=25°C and μ=0.1 mol dm−3 (NaNO3) in dioxane-water mixtures. The mixed-ligand complexes of copper(II) with OTC as primary ligand and amino acids or DNA constituents as secondary ligands were investigated in 50% v/v dioxane-water mixture. The formation constants of the complexes formed in solutions and their concentration distributions as a function ofpH were evaluated. The relative stabilities of the ternary and corresponding binary complexes were also studied.

    • Author Affiliations


      S M El-Medani1

      1. Department of Chemistry, Faculty of Science, El-Faiyum, Cairo University, Egypt
    • Dates

  • Journal of Chemical Sciences | News

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