• Design of biofunctional molecular and supramolecular systems: Membrane transport models

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    • Keywords


      Biofunctional systems; membrane transport models; substrate affinity

    • Abstract


      Cell membranes show a variety of functions that are essential for cell survival. Among them, active transport is a typical high functionality that the biomembrane system has realized. To understand and mimic the functionality of the biomembrane transport systems, carrier-mediated active transport systems are studied. Affinity switching of the carrier, i.e., high substrate affinity in the extraction and low affinity in the release processes, is the effective approach to achieve artificial active transport. Free energy to drive this active transport is supplied in the affinity-swtiching process. This paper describes our recent results on design and performance of novel molecular and supramolecular active transport systems, in which carriers are designed by the affinity-switching concept.

    • Author Affiliations


      Koji Araki1

      1. Institute of Industrial Science, University of Tokyo, 7-22-1 Roppongi, Minato-ku, Tokyo - 106, Japan
    • Dates

  • Journal of Chemical Sciences | News

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