• Studies on organometallic compounds: An approach towards characterisation of structure and activity of triorganostannyl 2-(arylazo)benzenecarboxylates in relation to the bacterial cell wall

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      https://www.ias.ac.in/article/fulltext/jcsc/105/03/0183-0187

    • Keywords

       

      Organometallics; triorganostannyl 2-(arylazo)benzenecarboxylates; tri-n-butyl-stannyl carboxylates; biologicall active; intercalation; CPK space-filling models; computer molecular model

    • Abstract

       

      Organostannyl 2-(arylazo)benzenecarboxylates have shown great promise in inhibiting the growth of Gram-positive bacteria. A possible explanation for the structure-activity relationship (SAR) has been discussed through an intercalation mechanism. The intercalative binding mechanism finds support from spectral, chemical as well as X-ray computer molecular modelling evidences. An interpretation of the activity against various microorganisms has also been made in the present investigation.

    • Author Affiliations

       

      B B Maji1 S Pain2 G Biswas2 3 K L Ghatak4 S N Ganguly5 Asok Banerjee2

      1. Department of Chemistry, Presidency College, Calcutta - 700 073, India
      2. Department of Biophysics, Bose Institute, Calcutta - 700 054, India
      3. Department of Physics, Balurghat College, Dist. South Dinajpur, P.O. Balurghat - 733 101, India
      4. Department of Chemistry, Durgapur Government College, Durgapur - 713 213, India
      5. Department of Botany, Bose Institute, Calcutta - 700 009, India
    • Dates

       
  • Journal of Chemical Sciences | News

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