• A study of ethoxymethylation in the 3-position of chroman-4-ones

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/103/01/0025-0031

    • Keywords

       

      Hydroxy- and methoxy-chromanones; 3-bis-hydroxymethyl chromanones; ethoxymethylation

    • Abstract

       

      Ethoxymethylation of 7-hydroxy- (1) and 7-methoxy (6a) -chroman-4-ones with ethoxymethl chloride in the presence of anhydrous potassium carbonate and acetone results in formation of 3,3-bis-hydroxymethyl derivatives (3 and7) in very good yields, and not the expected 3-hydroxymethyl derivatives. But 5,7-dimethoxychroman-4-one (6b) does not react with ethoxymethyl chloride under the same conditions.

    • Author Affiliations

       

      Amolak C Jain1 Rene Saksena1

      1. Department of Chemistry, University of Delhi, Delhi - 110 007, India
    • Dates

       
  • Journal of Chemical Sciences | News

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