• Organo-lithiation and halogen metal exchange reactions in organic synthesis-an anomolous aromatic substitution via halogen-metal exchange

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/100/02-03/0205-0215

    • Keywords

       

      Organolithiation; metal-halogen exchange; anomalous substitution and mechanism.

    • Abstract

       

      Synthesis via organo-lithium compounds is reviewed. An anomalous aromatic substitution via halogen-metal exchange is described. Here, the substitution does not occur at the position where the halogen was present; but at an alternate position. A mechanism is advanced, in which the halogen-metal exchange is proposed as being faster than the hydrogen(acidic)-metal exchange.

    • Author Affiliations

       

      N S Narasimhan1 R R Joshi1

      1. Garware Research Centre.Department of Chemistry, University of Poona, Pune - 411007, India
    • Dates

       
  • Journal of Chemical Sciences | News

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