• QSAR studies on estrogen receptor binding affinity of 2-phenylindoles using first-order valence molecular connectivity

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    • Keywords


      Quantitative structure-activity relationship; 2-phenylindoles; estrogen receptor binding affinity; molecular connectivity

    • Abstract


      The estrogen receptor binding affinity of 2-phenylindoles is found to be significantly correlated with Kier’s first-order valence molecular connectivity index. The correlation equations obtained provide a much simple rationale to design more potent compounds and help in predicting the potency of new compounds.

    • Author Affiliations


      P Singh1

      1. Department of Chemistry, Birla Institute of Technology and Science, Pilani - 333 031, India
    • Dates

  • Journal of Chemical Sciences | News

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