• QSAR studies on estrogen receptor binding affinity of 2-phenylindoles using first-order valence molecular connectivity

    • Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jcsc/097/01/0091-0095

    • Keywords

       

      Quantitative structure-activity relationship; 2-phenylindoles; estrogen receptor binding affinity; molecular connectivity

    • Abstract

       

      The estrogen receptor binding affinity of 2-phenylindoles is found to be significantly correlated with Kier’s first-order valence molecular connectivity index. The correlation equations obtained provide a much simple rationale to design more potent compounds and help in predicting the potency of new compounds.

    • Author Affiliations

       

      P Singh1

      1. Department of Chemistry, Birla Institute of Technology and Science, Pilani - 333 031, India
    • Dates

       
  • Journal of Chemical Sciences | News

© 2021-2022 Indian Academy of Sciences, Bengaluru.