Two-dimensional nuclear Overhauser effect in biomolecules
During the last 5 years, since its first application to biomolecules, two-dimensional nuclear Overhauser effect (2DNOE) has become an extremely powerful technique for assignment ofNMR spectra and for elucidation of conformation of biomolecules in solution.
The methodology of the 2DNOE technique, its recent developments and its applications to proteins and oligonucleotides are briefly reviewed.
Volume 134, 2022
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