• Facile chlorination of acetophenone by chloramine-T in the cationic micellar phase

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      https://www.ias.ac.in/article/fulltext/jcsc/093/05/0849-0854

    • Keywords

       

      Chlorination of ketone; chloramine-T; micellar phase; mineral acid

    • Abstract

       

      The chlorination of acetophenone by chloramine-T (cat) has been catalysed by added detergents, sodium laurylsulphate (NaLS) and cetyltrimethylammonium bromide (ctab). Phenacyl chloride is the exclusive product of the reaction and the % yield of the product is greater in the cationic micellar phase indicating facile chlorination in this media (even in the absence of the mineral acid). Using Piszkiewicz’s treatment, the positive cooperativity for the micellar catalysed reactions has been calculated. At the cationic micellar phase ofctab, the interaction between ammonium ion and phenyl and methylene groups probably leads to greater stabilisation than the simple hydrophobic association encountered in the micelle interior of NaLS.

    • Author Affiliations

       

      P S Raghavan1 Vangalur S Srinivasan1

      1. Department of Chemistry, Ramakrishna Mission, Vivekananda College, Mylapore, Madras - 600 004, India
    • Dates

       
  • Journal of Chemical Sciences | News

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