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    • Keywords


      5-Acyl-2-dialkylaminothiazoles; 2-morpholinothiazole-5-carboxylic ester

    • Abstract


      Amidinothioureas (7), (11) and (12) obtained by condensation of N,N-disubstituted thioureas with amide acetals have been used as starting materials for the synthesis of thiazoles. Thus, reaction with chloracetone and phenacyl bromides leads to ketones; the use of chloracetic ester in this reaction yields the thiazole-5-carboxylic ester (10).

    • Author Affiliations


      S Rajappa1 V Sudarsanam2 B G Advani1 A V Rane1

      1. CIBA-GEIGY Research Centre, Goregaon, Bombay - 400 063, India
      2. The Boots Company (India) Ltd., SION, Bombay - 400 022, India
    • Dates

  • Journal of Chemical Sciences | News

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