• Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/046/0022

    • Keywords

       

      SARS-CoV-2; COVID-19; genomics; variants; sequencing; clades

    • Abstract

       

      Since its emergence as a pneumonia-like outbreak in the Chinese city of Wuhan in late 2019, the novelcoronavirus disease COVID-19 has spread widely to become a global pandemic. The first case of COVID-19in India was reported on 30 January 2020 and since then it has affected more than ten million people andresulted in around 150,000 deaths in the country. Over time, the viral genome has accumulated mutations as itpasses through its human hosts, a common evolutionary mechanism found in all microorganisms. This hasimplications for disease surveillance and management, vaccines and therapeutics, and the emergence ofreinfections. Sequencing the viral genome can help monitor these changes and provides an extraordinaryopportunity to understand the genetic epidemiology and evolution of the virus as well as tracking its spread in apopulation. Here we review the past year in the context of the phylogenetic analysis of variants isolated overthe course of the pandemic in India and highlight the importance of continued sequencing-based surveillance inthe country.

    • Author Affiliations

       

      SURABHI SRIVASTAVA1 SOFIA BANU1 PRIYA SINGH1 DIVYA TEJ SOWPATI1 RAKESH K MISHRA1

      1. CSIR–Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, Telangana 500 007, India
    • Dates

       
  • Journal of Biosciences | News

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2021-2022 Indian Academy of Sciences, Bengaluru.