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AMPK; histone modification; histone PTMs; metabolic rewiring; nutritional stress; stressresponse

Under nutritional stress, cells undergo metabolic rewiring that results in changes of various cellular processesthat include gene transcription. This transcriptional regulation requires dynamic chromatin remodeling thatinvolves histone post-translational modifications. There are several histone marks that may act as switchesupon starvation for stress-response pathways.

JAEHYOUN LEE¹ SEUNGHEE OH¹ SUSAN M ABMAYR^{1 2} JERRY L WORKMAN¹

1. Stowers Institute for Medical Research, Kansas City, MO 64110, USA
2. Department of Anatomy and Cell Biology, University of Kansas School of Medicine, Kansas City, KS 66160, USA

Published

20 January 2020