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      https://www.ias.ac.in/article/fulltext/jbsc/044/04/0084

    • Keywords

       

      Biopolymers; gene delivery; gene therapy; vectors; virus

    • Abstract

       

      The success of viral vectors mediated gene therapy is still hampered by immunogenicity and insufficient transgeneexpression. Alternatively, non-viral vectors mediated gene delivery has the advantage of low immunogenicity despiteshowing low transgene expression. By carefully considering the advantages of each approach, hybrid vectors are currentlybeing developed by modifying the viral vectors using non-viral biopolymers. This review provides an overview of thehybrid vectors currently being developed.

    • Author Affiliations

       

      BALAJI BALAKRISHNAN1 ERNEST DAVID2

      1. Department of Haematology, Christian Medical College, Vellore 632004, Tamil Nadu, India
      2. Department of Biotechnology, Thiruvalluvar University, Vellore 632115, Tamil Nadu, India
    • Dates

       
  • Journal of Biosciences | News

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      Posted on July 25, 2019

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